3/23/2023 0 Comments Clc sequence viewer referenceAlthough there are several reports about the prevalence of intestinal sarcocystosis in humans from different regions of the world, there is no published data about identified species causing intestinal infections using molecular methods in Iran. Sarcocystis is not usually considered as an important enteric pathogen in immunocompromised patients but a report has been published on intestinal sarcocystosis-associated cholecystitis in Iran. For example, Sarcocystis-associated acute enteritis was reported in 6 cases in Thailand. In some countries, infection has potential public health importance, because humans may acquire infection by consumption of raw or under-Ĭooked beef or pork causing intestinal sarcocystosis. In humans, infection occurs from eating uncooked or poorly cooked meat of some livestock with infective stages (sarcocysts) and the sexual phase (gametogony) occurs in the intestinal mucosa. Sarcocystis protozoa of the intestinal tract in humans as the final host (excretion of sporocysts with feces) have a similar life cycle. Depending on the species of Sarcocystis, these parasites are causative agents of intestinal or muscular sarcocystosis in human beings. Since the first report of Sarcocystis infection, more than 120 species have been identified in this genus. Sarcocystosis is an intracellular protozoan parasitic disease caused by coccidia of the genus Sarcocystis. Intestinal parasites, both protozoa and helminths, are 2 main enteric pathogens in developing countries, and some of these are responsible for emerging and reemerging infections in immunodeficient patients. Key words: Sarcocystis cruzi, PCR, sporocyst, diarrhea, human, AIDS To the best of our knowledge, this is the first report of S. Sarcocystis-like sporocysts found from a woman were identified as Sarcocystis cruzi through 18S rDNA amplification and phylogenetic analysis. Isospora belli), 2 Cyclospora cayetanensis, and 15 microsporidia (Enterocytozoon bieneusi). Oocysts-positive samples were 68 Cryptosporidium spp., 9 Cystoisospora belli (syn. Diarrheal samples of 741 immunodeficient patients with recurrent persistent or chronic diarrhea were examined by microscopy and molecular biological analysis. This study aimed to address how to detect and differentiate Sarcocystis oocysts and/or sporocysts from enteric protozoans in the diarrheal samples of immunodeficient patients in Shiraz, Iran. It might be expected that species for which humans are the final host (Sarcocystis hominis and Sarcocystis suihominis as well as possibly others) would be encountered increasingly often in immunodeficient persons. Prevalence of Enteric Protozoan Oocysts with Special Reference to Sarcocystis cruzi among Fecal Samples of Diarrheic Immunodeficient Patients in Iran Mahmoud Agholi1,2, Shahrbanou Naderi Shahabadi3, Mohammad Hossein Motazedian4, Gholam Reza Hatam4,* HIV/AIDS Research Center, Fasa University of Medical Sciences, Fasa, Iran 2Department of Microbiology, Fasa University of Medical Sciences, Fasa, Iran 3Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran 4Basic Sciences in Infectious Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran 1Ībstract: The genus Sarcocystis is not usually considered as an important enteric pathogen in immune compromised patients.
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